Western Blot analysis of various cells using E-cadherin Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of various cells using E-cadherin Polyclonal Antibody at dilution of 1:1000.
E-cadherin Polyclonal Antibody
E-AB-31261
Product group Antibodies
Overview
- SupplierElabscience
- Product NameE-cadherin Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierWB,IHC,IF,ELISA
- CertificationResearch Use Only
- Concentration1 mg/ml
- Scientific DescriptionThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.
- UNSPSC12352203