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(E)-KN-93 (phosphate)

HY-110140
MedChem Express
CAS Number1188890-41-6
Product group Chemicals
Estimated Purity99.85
Molecular Weight599.03
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Overview

  • Supplier
    MedChem Express
  • Product Name
    (E)-KN-93 (phosphate) [1188890-41-6]
  • Delivery Days Customer
    5
  • CAS Number
    1188890-41-6
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C26H32ClN2O8PS
  • Molecular Weight
    599.03
  • Scientific Description
    (E)-KN-93 phosphate is an inhibitor for Ca 2+ /calmodulin-dependent protein kinase II ( CaMK II ) with IC 50 of 9 microM and 3 microM, for CaMKIIdelta monomer and CaMKIIdelta dodecamer. (E)-KN-93 phosphate binds competitively with Ca 2+ /CaM, and disrupts their interaction with CaMK II, and thus inhibits the CaMK II activation [1] .
  • SMILES
    O=P(O)(O)O.O=S(N(C1=C(C=CC=C1)CN(C)C/C=C/C2=CC=C(C=C2)Cl)CCO)(C3=CC=C(C=C3)OC)=O
  • Storage Instruction
    RT
  • UNSPSC
    12352200

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