(E)-KN-93 (phosphate)
HY-110140
CAS Number1188890-41-6
Product group Chemicals
Estimated Purity99.85
Molecular Weight599.03
Overview
- SupplierMedChem Express
- Product Name(E)-KN-93 (phosphate) [1188890-41-6]
- Delivery Days Customer5
- CAS Number1188890-41-6
- CertificationResearch Use Only
- Estimated Purity99.85
- Molecular FormulaC26H32ClN2O8PS
- Molecular Weight599.03
- Scientific Description(E)-KN-93 phosphate is an inhibitor for Ca 2+ /calmodulin-dependent protein kinase II ( CaMK II ) with IC 50 of 9 microM and 3 microM, for CaMKIIdelta monomer and CaMKIIdelta dodecamer. (E)-KN-93 phosphate binds competitively with Ca 2+ /CaM, and disrupts their interaction with CaMK II, and thus inhibits the CaMK II activation [1] .
- SMILESO=P(O)(O)O.O=S(N(C1=C(C=CC=C1)CN(C)C/C=C/C2=CC=C(C=C2)Cl)CCO)(C3=CC=C(C=C3)OC)=O
- Storage InstructionRT
- UNSPSC12352200