E1231
HY-117006
CAS Number1031195-19-3
Product group Chemicals
Estimated Purity98.55
Molecular Weight363.41
Overview
- SupplierMedChem Express
- Product NameE1231 [1031195-19-3]
- Delivery Days Customer10
- CAS Number1031195-19-3
- CertificationResearch Use Only
- Estimated Purity98.55
- Molecular FormulaC21H21N3O3
- Molecular Weight363.41
- Scientific DescriptionE1231 is an orally active activator of Sirtuin 1 ( SIRT1 ) ( EC 50 =0.83 microM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (K D =9.61 microM) and deacetylated liver X receptor-alpha ( LXRalpha ), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE -/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases [1] .
- SMILESCC(N1CCN(C(C2=CC(C3=CC=C(C)O3)=NC4=CC=CC=C24)=O)CC1)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200