E1231
HY-117006
CAS Number1031195-19-3
Product group Chemicals
Estimated Purity98.55
Molecular Weight363.41
Overview
- SupplierMedChem Express
- Product NameE1231 [1031195-19-3]
- Delivery Days Customer10
- CAS Number1031195-19-3
- CertificationResearch Use Only
- Estimated Purity98.55
- Molecular FormulaC21H21N3O3
- Molecular Weight363.41
- Scientific DescriptionE1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 microM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 microM) and deacetylated liver X receptor-alpha (LXRalpha), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE-/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases[1].
- SMILESCC(N1CCN(C(C2=CC(C3=CC=C(C)O3)=NC4=CC=CC=C24)=O)CC1)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200
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E1231 [1031195-19-3]T9106
CAS Number1031195-19-3
Estimated Purity98.86%
Molecular Weight363.41
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Product group Chemicals
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CAS Number1031195-19-3
Estimated Purity98.86%
Molecular Weight363.41
- SizePrice