E197 [2378515-04-7]

TargetMol Chemicals

E197 [2378515-04-7]

86

Chemical

Research Use Only

E197

C19H21ClN2O3S

392.9

E197 is a DOCK5 inhibitor. E197 can inhibit both mouse and human osteoclast activity. In particular, E197 prevented pathological bone loss in mice. Most interestingly, treatment with E197 did not affect osteoclast and osteoblast numbers and hence did not impair bone formation. E197 could represent a lead molecule to develop new antiosteoporotic drugs targeting the mechanism of osteoclast adhesion onto the bone.

3 years

O=S1(=O)[C@@]2([C@@H](O)CN1C3=CC=CC=C3)CN(CC4=CC=C(Cl)C=C4)CC2

-20°C

12352200