
FACS analysis of ZR-75-1 cells using GTX80623 E2F5 antibody, N-term. Top histogram : negative control Bottom histogram : ZR-75-1 cells
E2F5 antibody, N-term
GTX80623
Overview
- SupplierGeneTex
- Product NameE2F5 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:2000. IHC-P: 1:50-1:100. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID1875
- Target nameE2F5
- Target descriptionE2F transcription factor 5
- Target synonymsE2F transcription factor 5, p130-binding; E2F-5; transcription factor E2F5
- Protein IDQ15329
- Protein NameTranscription factor E2F5
- Scientific DescriptionThe protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203