E3 Ligase Ligand-linker Conjugate 101

MedChem Express

E3 Ligase Ligand-linker Conjugate 101

14

Research Use Only

C34H49N5O6S

655.85

E3 Ligase Ligand-linker Conjugate 101 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 101 can be used as a key intermediate for the synthesis of complete PROTAC molecules.

O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(C2CCN(CC2)CC(OC(C)(C)C)=O)=O)=O)NCC(C=C3)=CC=C3C(SC=N4)=C4C

41115800