E3 Ligase Ligand-linker Conjugate 103

MedChem Express

E3 Ligase Ligand-linker Conjugate 103

14

Research Use Only

C40H59N7O6S

766.00

E3 Ligase Ligand-linker Conjugate 103 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 Ligase Ligand-linker Conjugate 103 can be used as a key intermediate for the synthesis of complete PROTAC molecules.

O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(CN2CC3(CN(C3)CC4CCN(CC4)C(OC(C)(C)C)=O)C2)=O)=O)NCC(C=C5)=CC=C5C(SC=N6)=C6C

12352200