E3 Ligase Ligand-linker Conjugate 159

MedChem Express

E3 Ligase Ligand-linker Conjugate 159

5

Research Use Only

C37H53N7O7S2

771.99

E3 Ligase Ligand-linker Conjugate 159 is an E3 ligase ligand-linker conjugate. E3 Ligase Ligand-linker Conjugate 159 can be used for the synthesis of SMD-3236 (HY-170824), a PRAOTAC that targets the degradation of SMARCA2, exhibiting long-lasting antitumor activity in vivo[1].

O=C(N1[C@H](C(N[C@@H](CN2CCOCC2)C3=CC=C(C4=C(C)N=CS4)C=C3)=O)C[C@@H](O)C1)[C@H](C(C)(C)C)N5N=NC([C@H](CC6)CC[C@@H]6COS(C)(=O)=O)=C5

41115800