E3 ligase Ligand-Linker Conjugate 35

MedChem Express

E3 ligase Ligand-Linker Conjugate 35

14

Research Use Only

C37H55N7O6S

725.94

E3 ligase Ligand-Linker Conjugate 35 is a conjugate of E3 ligase ligand and linker, consisting of (S,R,S)-AHPC (HY-125845) and the corresponding Linker. (S,R,S)-AHPC is a VH032-based von Hippel-Lindau (VHL) ligand that recruits VHL proteins. E3 ligase Ligand-Linker Conjugate 35 can be used as a key intermediate for the synthesis of complete PROTAC molecules.

O=C([C@H]1N(C[C@@H](C1)O)C([C@H](C(C)(C)C)NC(CN2CC(C2)CN3CCN(CC3)C(OC(C)(C)C)=O)=O)=O)NCC(C=C4)=CC=C4C(SC=N5)=C5C

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