E6446

AbMole BioScience

E6446

9

1219925-73-1

Research Use Only

C27H35N3O3

449.59

E6446 is an inhibitor of Toll-like receptor (TLR) 7 and 9 signaling in a variety of human and mouse cell types and inhibits DNA-TLR9 interactions in vitro. E6446 is also a potent SCD1 inhibitor (KD: 4.61 uM), significantly inhibiting adipogenic differentiation and hepatic lipogenesis through SCD1-ATF3 signaling.

2-8°C, dry, sealed

12352200