E7090 succinate

Biorbyt

E7090 succinate [1879965-80-6]

10

1879965-80-6

Research Use Only

98.00%

C32H37N5O6.3/2C4H6O4

764.82

E7090 succinate is a selective, potent, orally-administered inhibitor of FGFR1, FGFR2, and FGFR3 tyrosine kinase activities, demonstrating IC50 values of 0.71 nM (FGFR1), 0.50 nM (FGFR2), 1.2 nM (FGFR3), and 120 nM (FGFR4).

O=C(CCC(O)=O)O.O=C(C1=CC=C(C2CCN(CC2)CCO)C=C1)NC3=NC=CC(OC4=CC5=C(C=C4OCCOC)N(C(NC)=O)C=C5)=C3.O=C(CCC(O)=O)O.O=C(C6=CC=C(C7CCN(CC7)CCO)C=C6)NC8=NC=CC(OC9=CC%10=C(C=C9OCCOC)N(C(NC)=O)C=C%10)=C8.O=C(CCC(O)=O)O

-20°C

12352200