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E7820

HY-14571
MedChem Express
CAS Number289483-69-8
DownloadMSDS
Product group Chemicals
Estimated Purity99.06
Molecular Weight336.37
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Overview

  • Supplier
    MedChem Express
  • Product Name
    E7820 [289483-69-8]
  • Delivery Days Customer
    10
  • CAS Number
    289483-69-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.06
  • Molecular Formula
    C17H12N4O2S
  • Molecular Weight
    336.37
  • Scientific Description
    E7820 (ER68203-00), an orally active aromatic sulfonamide derivative, is a unique angiogenesis inhibitor suppressing an expression of integrin alpha2 subunit on endothelium. E7820 inhibits rat aorta angiogenesis with an IC50 of 0.11 microg/ml. E7820 modulates alpha-1, alpha-2, alpha-3, and alpha-5 integrin mRNA expression. Antiangiogenic and antitumor activity[1][2].
  • SMILES
    O=S(C1=CC(C#N)=CC=C1)(NC2=C(NC=C3C#N)C3=C(C)C=C2)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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