Bio-Connect

EAI045

HY-100213
MedChem Express
CAS Number1942114-09-1
Product group Chemicals
Estimated Purity99.08
Molecular Weight383.40
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Overview

  • Supplier
    MedChem Express
  • Product Name
    EAI045 [1942114-09-1]
  • Delivery Days Customer
    5
  • CAS Number
    1942114-09-1
  • Estimated Purity
    99.08
  • Molecular Formula
    C19H14FN3O3S
  • Molecular Weight
    383.40
  • Scientific Description
    EAI045 is an allosteric and the fourth-generation inhibitor of mutant EGFR with IC 50 s of 1.9, 0.019, 0.19 and 0.002 microM for EGFR, EGFR L858R , EGFR T790M and EGFR L858R/T790M at 10 microM ATP, respectively.
  • SMILES
    O=C(C(C1=C(O)C=CC(F)=C1)N2C(C(C=CC=C3)=C3C2)=O)NC4=NC=CS4
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200