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EAI045

M6081
AbMole BioScience
CAS Number1942114-09-1
Product group Chemicals
Molecular Weight383.40
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    EAI045
  • Delivery Days Customer
    9
  • CAS Number
    1942114-09-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C19H14FN3O3S
  • Molecular Weight
    383.40
  • Scientific Description
    EAI045 is a fourth generation allosteric inhibitor of mutant EGFR, which inhibits EGFR at 10 uM ATP, EGFRL858R, EGFRT790M and EGFRL858R/T790M with IC50 values of 1.9, 0.019, 0.19 and 0.002 uM respectively.
  • SMILES
    OC1=CC=C(F)C=C1C(N2CC3=C(C=CC=C3)C2=O)C(=O)NC4=NC=CS4
  • UNSPSC
    12352200

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