Ebselen oxide

MedChem Express

Ebselen oxide [104473-83-8]

10

104473-83-8

Research Use Only

98.0

C13H9NO2Se

290.18

Ebselen oxide, the selenone analogue of Ebselen, covalently modifies diguanylate cyclase (DGC) to inhibit c-di-GMP-receptor interactions and reduces DGC activity. Ebselen oxide also inhibits alginate production (IC50=14 microM) by Pseudomonas aeruginosa. Ebselen oxide inhibits HDAC1, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8, and HDAC9 (IC50 ranging from 0.2 to 4.7 microM)[1][2][3].

O=[Se]1N(C(C2=C1C=CC=C2)=O)C3=CC=CC=C3

-20°C

12352200