EC359

MedChem Express

EC359 [2012591-09-0]

10

2012591-09-0

Research Use Only

99.09

C36H38F2O2

540.68

EC359 is a potent, selective, high affinity and orally active leukemia inhibitory factor receptor (LIFR) inhibitor with a K d of 10.2 nM, which directly interacts with LIFR to effectively block LIF/ LIFR interactions [1] . EC359 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

C[C@@]12[C@](O)(C(F)(F)C#C)CC[C@@]1([H])[C@]3([H])CCC4=CC(CCC4=C3[C@@H](C5=CC=C(C6=C(C)C=C(C)C=C6C)C=C5)C2)=O

-20°C,2°C to 8°C

12352200