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ProductsBack/Ecdysone [3604-87-3]
Chemical Structure
Chemical Structure
Chemical Structure

Ecdysone [3604-87-3]

Research Use Only
AG-CN2-0071
AdipoGen Life Sciences
CAS Number3604-87-3
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight464.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Ecdysone
  • Delivery Days Customer
    10
  • CAS Number
    3604-87-3
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C27H44O6
  • Molecular Weight
    464.6
  • Scientific Description
    Chemical. CAS: 3604-87-3. Formula: C27H44O6. MW: 464.6. Isolated from Ipomoea hederacea. Steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone. A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Appears in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides. - Steroidal prohormone of the major insect molting hormone 20-hydroxyecdysone. A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. Induces the expression of genes coding for proteins that the larva requires, and it causes chromosome puffs (sites of high expression) to form in polytene chromosomes. Plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in moulting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP). Appears in many plants mostly as a protection agent (toxins or antifeedants) against herbivorous insects. Used for controlled gene expression in scientific research, agriculture and medicine. Used for the development of selective insect growth regulators for use as environmentally benign insecticides.
  • SMILES
    [H][C@@](C)([C@H](O)CCC(C)(C)O)[C@@]1([H])CC[C@@]2(O)C3=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]4(C)C3CC[C@]12C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Ecdysone, an insect steroid hormone, and its mode of action: P. Karlson & C.E. Sekeris; Recent Prog. Horm. Res. 22, 473 (1966)
  • Ecdysone, the molting hormone of insects: P. Karlson; Naturwissenschaften 53, 445 (1966) (German)
  • Puffs and gene regulation-molecular insights into the Drosophila ecdysone regulatory hierarchy: C.S. Thummel; Bioessays 12, 561 (1990)
  • Hormones, puffs and flies: the molecular control of metamorphosis by ecdysone: A.J. Andres & C.S. Thummel; Trends Genet. 8, 132 (1992) (Review)
  • The IVth Karlson Lecture: ecdysone-responsive genes: P. Cherbas; Insect Biochem. Mol. Biol. 23, 3 (1993)
  • Ecdysone signaling cascade and regulation of Drosophila metamorphosis: E.H. Baehrecke; Arch. Insect Biochem. Physiol. 33, 231 (1996) (Review)
  • Nuclear hormone receptors and the Drosophila ecdysone response: S.R. Russell; Biochem. Soc. Symp. 62, 111 (1996)
  • Ecdysone receptors and their biological actions: L.M. Riddiford, et al.; Vitam. Horm. 60, 1 (2000)
  • Ecdysone-regulated puff genes 2000: C.S Thummel; Insect Biochem. Mol. Biol. 32, 113 (2002)
  • Ecdysone-controlled expression of transgenes: L.D. Graham; Expert Opin. Biol. Ther. 2, 525 (2002)