eCF506 [1914078-41-3]

MedChem Express

eCF506 [1914078-41-3]

10

1914078-41-3

Research Use Only

99.77

C26H38N8O3

510.63

eCF506 (NXP900) is a highly potent and orally active YES1/SRC kinase inhibitor with an IC50 of 0.47 nM. eCF506 locks its target into its native closed conformation, thereby inhibiting both kinase activity and complex formation with protein partners. eCF506 can be used for the study of esophageal squamous cancer and breast cancer[1].

NC1=C2C(C3=CC(OC)=C(NC(OC(C)(C)C)=O)C=C3)=NN(CCN4CCC(N(C)C)CC4)C2=NC=N1

-20°C,2°C to 8°C

12352200