Ecopipam (hydrochloride) [190133-94-9]

MedChem Express

Ecopipam (hydrochloride) [190133-94-9]

10

190133-94-9

Research Use Only

99.46

C19H21Cl2NO

350.28

Ecopipam (SCH 39166) hydrochloride is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. Ecopipam hydrochloride shows more than 40-flod selectivity over D2, D4, 5-HT, and alpha2a receptor (Ki=0.98, 5.52, 0.08, and 0.73 microM, respectively). Ecopipam hydrochloride can be used for the research of schizophrenia and obesity[1][3].

OC1=C(Cl)C=C2C([C@]3([H])[C@@](CCC4=C3C=CC=C4)([H])N(C)CC2)=C1.[H]Cl

2°C to 8°C

12131703