Efavirenz-d5

MedChem Express

Efavirenz-d5 [1132642-95-5]

10

1132642-95-5

Research Use Only

C14H4D5ClF3NO2

320.71

Efavirenz-d 5 (DMP 266-d5) is the deuterium labeled Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture[1]. Efavirenz-d5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

C(#CC1(C(C1([2H])[2H])([2H])[2H])[2H])[C@@]2(C(F)(F)F)C=3C(NC(=O)O2)=CC=C(Cl)C3

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