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EG01377 (dihydrochloride) [2749438-61-5]

HY-112151A
MedChem Express
CAS Number2749438-61-5
Product group Chemicals
Estimated Purity98.98
Molecular Weight659.60
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Overview

  • Supplier
    MedChem Express
  • Product Name
    EG01377 (dihydrochloride) [2749438-61-5]
  • Delivery Days Customer
    5
  • CAS Number
    2749438-61-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.98
  • Molecular Formula
    C26H32Cl2N6O6S2
  • Molecular Weight
    659.60
  • Scientific Description
    EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 microM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects[1].
  • SMILES
    O=S(C1=CC(C2=CC=C(CN)C=C2)=CC3=C1OCC3)(NC4=C(C(N[C@@H](CCC/N=C(N)/N)C(O)=O)=O)SC=C4)=O.Cl.Cl
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200