EGFR-IN-37

MedChem Express

EGFR-IN-37

10

Research Use Only

C26H25ClN6O2

488.97

EGFR-IN-37 is a potent inhibitor of EGFR. EGFR-IN-37 is an anti-tumor agent with low toxic side effects. EGFR-IN-39 is an acrylamide derivative compound. Overexpression and mutation of the epidermal growth factor receptor (EGFR) has been clearly demonstrated to lead to uncontrollable cell growth and is associated with the progression of most cancer diseases, especially NSCLC. EGFR-IN-37 has the potential for the research of diseases associated with EGFR mutations (extracted from patent WO2021185348A1, compound 7)[1].

NC1=NC=CN2C([C@@]3([H])CN(CCC3)C(C=C)=O)=NC(C4=CC(Cl)=C(C=C4)OCC5=CC=CC=N5)=C12

12352200