EGFR-IN-49 [2459932-81-9]

MedChem Express

EGFR-IN-49 [2459932-81-9]

10

2459932-81-9

Research Use Only

C22H15N5O2S

413.45

EGFR-IN-49 is a potent and selective EGFR inhibitor with IC50s of 65.0 nM and 13.6 nM for EGFRT790M and EGFRT790M/L858R, respectively. EGFR-IN-49 induces late apoptosis in a dose-dependent manner[1].

C=CC(NC1=CC(OC2=NC(NC3=CC=CC(C#N)=C3)=NC4=C2SC=C4)=CC=C1)=O

12131703