EGFR-IN-50 [2044508-48-5]
HY-146210
CAS Number2044508-48-5
Product group Chemicals
Molecular Weight564.51
Overview
- SupplierMedChem Express
- Product NameEGFR-IN-50 [2044508-48-5]
- Delivery Days Customer10
- CAS Number2044508-48-5
- CertificationResearch Use Only
- Molecular FormulaC24H26BrN3O4S2
- Molecular Weight564.51
- Scientific DescriptionEGFR-IN-50 (Compound 9h) is a potent EGFR inhibitor against L858R resistance mutation (TEL-EGFR-L858R-BaF3: GI50=8 nM, TEL-EGFR-T790M-L858R-BaF3: GI50=6.03 microM). EGFR-IN-50 shows anti-proliferative activity to cancer cells[1].
- SMILESC=CCSSCCC(OCCCOC1=CC2=C(C(NC3=CC(Br)=CC=C3)=NC=N2)C=C1OC)=O
- UNSPSC12131703