EGFR-IN-51 [2418549-32-1]

MedChem Express

EGFR-IN-51 [2418549-32-1]

10

2418549-32-1

Research Use Only

C21H15N3O2S

373.43

EGFR-IN-51 (Compound 6) is a potent EGFR inhibitor with IC50 values of 0.493, 102.60 and 461.63 microM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-51 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].

S=C(NC1=C2C=CC=CC2=NC3=C1C=CC=C3)NC4=CC=C5OCOC5=C4

12131703