EGFR-IN-52 [454436-75-0]

MedChem Express

EGFR-IN-52 [454436-75-0]

10

454436-75-0

Research Use Only

C19H18N4O3S

382.44

EGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC50 values of 0.358, 86.02 and 432.67 microM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].

CC1=C(C(N(N1C)C2=CC=CC=C2)=O)NC(NC3=CC=C4OCOC4=C3)=S

12131703