EGFR-IN-52 [454436-75-0]
HY-146472
CAS Number454436-75-0
Product group Chemicals
Molecular Weight382.44
Overview
- SupplierMedChem Express
- Product NameEGFR-IN-52 [454436-75-0]
- Delivery Days Customer10
- CAS Number454436-75-0
- CertificationResearch Use Only
- Molecular FormulaC19H18N4O3S
- Molecular Weight382.44
- Scientific DescriptionEGFR-IN-52 (Compound 4) is a potent EGFR inhibitor with IC50 values of 0.358, 86.02 and 432.67 microM against EGFR, EGFR L858R-TK and EGFR T790M-TK, respectively. EGFR-IN-52 shows cytotoxic activity against cancer cell lines and induces apoptosis[1].
- SMILESCC1=C(C(N(N1C)C2=CC=CC=C2)=O)NC(NC3=CC=C4OCOC4=C3)=S
- UNSPSC12131703