EGFR-IN-56 [2477726-83-1]

MedChem Express

EGFR-IN-56 [2477726-83-1]

10

2477726-83-1

Research Use Only

C23H22N4O3S

434.51

EGFR-IN-56 (Compound 13a) is a potent EGFR inhibitor with IC50 values of 541.7 nM and 132.1 nM against EGFRT790M and EGFRT790M/L858R, respectively. EGFR-IN-56 blocks cancer cells in G2/M phase and induce into late apoptosis[1].

C=CC(NC1=CC=CC(OC2=C(CSCC3)C3=NC(NC4=CC=C(OC)C=C4)=N2)=C1)=O

12131703