EGFR-IN-7 [2267329-76-8]

MedChem Express

EGFR-IN-7 [2267329-76-8]

9

2267329-76-8

Research Use Only

99.76

C32H41BrN9O2P

694.60

EGFR-IN-7 is a potent, selective and orally active EGFR kinase inhibitor. EGFR-IN-7 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. EGFR-IN-7 can be used for the research of various cancers[1].

CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1

-20°C,2°C to 8°C

12352200