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WB analysis of EGF-treated A431 (A), EGF-treated NIH3T3 (B), EGF-treated PC12 (C) whole cell lysates using GTX32321 EGFR (phospho Thr654) antibody.
WB analysis of EGF-treated A431 (A), EGF-treated NIH3T3 (B), EGF-treated PC12 (C) whole cell lysates using GTX32321 EGFR (phospho Thr654) antibody.
WB analysis of EGF-treated A431 (A), EGF-treated NIH3T3 (B), EGF-treated PC12 (C) whole cell lysates using GTX32321 EGFR (phospho Thr654) antibody.

EGFR (phospho Thr654) antibody

GTX32321
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetEGFR
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Overview

  • Supplier
    GeneTex
  • Product Name
    EGFR (phospho Thr654) antibody
  • Delivery Days Customer
    9
  • Antibody Specificity
    The full-length EGFR includes the 24 aa signal peptide that is cleaved during EGFR maturation. The Thr654 of mature EGFR is equivalent to Thr678 of uncleaved EGFR.
  • Application Supplier Note
    WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID1956
  • Target name
    EGFR
  • Target description
    epidermal growth factor receptor
  • Target synonyms
    avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor; epidermal growth factor receptor tyrosine kinase domain; ERBB; ERBB1; erb-b2 receptor tyrosine kinase 1; ERRP; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP00533
  • Protein Name
    Epidermal growth factor receptor
  • Scientific Description
    The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • HUNK phosphorylates EGFR to regulate breast cancer metastasis. Williams CB et al., 2020 Jan, Oncogene
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