EGFR T790M/L858R-IN-2

Biorbyt

EGFR T790M/L858R-IN-2

10

Research Use Only

98.00%

C28H28FN7O

497.57

EGFRT790M/L858R-IN-2 is a potent, selective inhibitor of EGFRT790M/L858R, exhibiting IC50 values of 3.5 nM for EGFRT790M/L858R and 1290 nM for EGFR WT. This compound effectively decreases the expression of p-EGFR, P-AKT, P-ERK1/2, and induces apoptosis as well as cell cycle arrest in the G1 phase, demonstrating anti-cancer activity [1].

-20°C

12352200