EGFR/Akt-IN-1

MedChem Express

EGFR/Akt-IN-1

9

Research Use Only

C22H17N5O2S

415.47

EGFR/Akt-IN-1 (compound 17) is a potent inhibitor of EGFR/Akt , with the IC 50 s of 12.89 microM and 10.88 microM in A549 cells, respectively. EGFR/Akt-IN-1 arrestes the cell cycle at the S phase [1] .

N#CC1=CC=C(C2=CN3C(SC=C3CC(N/N=C/C4=CC=C(OC)C=C4)=O)=N2)C=C1

12352200