EGFR/DHFR-IN-1

MedChem Express

EGFR/DHFR-IN-1

5

Research Use Only

C24H26N4O5S2

514.62

EGFR/DHFR-IN-1 (Compound 10e) is a dual inhibitor of EGFR and DHFR with IC50s of 0.151 and 0.541 microM, respectively. EGFR/DHFR-IN-1 arrests the cell cycle at both G0-G1 and S phases[1].

O=C(N1CCN(CC1)CC(SC2=NC3=C(C(C)=C(S3)C(C)=O)C(N2C4=CC=CC=C4)=O)=O)OCC

12352200