EGFR/HER2-IN-5
HY-147994
Overview
- SupplierMedChem Express
- Product NameEGFR/HER2-IN-5 [1879071-97-2]
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC30H33ClN6O4
- Molecular Weight577.07
- Scientific DescriptionEGFR/HER2-IN-5 (compound 6h) is an orally active irreversible dual inhibitor. EGFR/HER2-IN-5 inhibits EGFR with an IC50 value of 1.01 nM and demonstrates potent EGFR kinase inhibitory activities on L858R and T790M mutations. EGFR/HER2-IN-5 has potent antitumor efficacy in vivo and can be used for lung cancer research[1].
- SMILESO=C(NC1=CC2=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)N=CN=C2C=C1OCCOCC)/C=C/CN(C)C
- UNSPSC12131703