Bio-Connect

EGFR/HER2-IN-5

HY-147994
MedChem Express
Molecular Weight577.07
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    EGFR/HER2-IN-5 [1879071-97-2]
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Molecular Formula
    C30H33ClN6O4
  • Molecular Weight
    577.07
  • Scientific Description
    EGFR/HER2-IN-5 (compound 6h) is an orally active irreversible dual inhibitor. EGFR/HER2-IN-5 inhibits EGFR with an IC50 value of 1.01 nM and demonstrates potent EGFR kinase inhibitory activities on L858R and T790M mutations. EGFR/HER2-IN-5 has potent antitumor efficacy in vivo and can be used for lung cancer research[1].
  • SMILES
    O=C(NC1=CC2=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)N=CN=C2C=C1OCCOCC)/C=C/CN(C)C
  • UNSPSC
    12131703