EGFR/HER2-IN-6
HY-151156
Molecular Weight387.46
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameEGFR/HER2-IN-6
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC18H21N5O3S
- Molecular Weight387.46
- Scientific DescriptionEGFR/HER2-IN-6 (compound 43) is an EGFR/HER2 and DHFR inhibitor. EGFR/HER2-IN-6 inhibits EGFR kinase, HER2 kinase and DHFR with IC50s of 0.122, 0.078 and 0.585 microM, respectively. EGFR/HER2-IN-6 shows anticancer activity against several cancer cell lines with high safety profile and selectivity indices. EGFR/HER2-IN-8 can be used for the research of cancer[1].
- SMILESO=C(C1=CSC2=NC(CN3CCOCC3)=C(C4=CC=C(OC)C=C4)N21)NN
- UNSPSC12352200