EGFR/HER2-IN-7

MedChem Express

EGFR/HER2-IN-7 [2820126-28-9]

10

Research Use Only

C19H21N3O2S

355.45

EGFR/HER2-IN-7 is a potent anticancer agent with high selectivity against MCF-7 breast cancer cells. EGFR/HER2-IN-7 is a EGFR/HER2 kinase and DHFR inhibitor, with IC50s of 0.18 microM (EGFR), 0.146 microM (HER2), respectively. EGFR/HER2-IN-7 shows moderate inhibition on DHFR (IC50=0.907 microM)[1].

O=C(C1=CSC2=NC(CN3CCCCC3)=C(C4=CC=C(C)C=C4)N21)O

12131703