EGFR/HER2/DHFR-IN-1

TargetMol Chemicals

EGFR/HER2/DHFR-IN-1

107

Chemical

EGFR/HER2/DHFR-IN-1

C14H11BrN4O2S

379.23

EGFR/HER2/DHFR-IN-1 is a highly selective and potent anticancer compound specifically targeting MCF-7 breast cancer cells. It acts as a multi-inhibitor, targeting the EGFR/HER2 kinase and DHFR enzymes, with IC50 values of 0.153 uM, 0.108 uM, and 0.291 uM, respectively. Its mechanism of action involves cell cycle arrest at the G1/S phase and induction of apoptosis in cells [1].

3 years

#Reference to error in column [smiles]

-20°

12352200