EGFR/HER2/TS-IN-1 [2444363-11-3]

MedChem Express

EGFR/HER2/TS-IN-1 [2444363-11-3]

10

2444363-11-3

Research Use Only

C24H15N5O4S2

501.54

EGFR/HER2/TS-IN-1 (Compound 4d) is an EGFR, HER2 and TS (Thymidylate synthase) inhibitor with IC50 values of 0.203, 0.088 and 0.168 microM against EGFR, HER2 and TS, respectively. EGFR/HER2/TS-IN-1 induces MCF7 cell apoptosis[1].

N#CC1=C(C2=COC3=C(C2=O)C=CC=C3)NC(SCC(NC4=NC5=C(S4)C=C(C)C=C5)=O)=NC1=O

12131703