EGFR/HER2/TS-IN-2 [2444364-04-7]
HY-146239
Overview
- SupplierMedChem Express
- Product NameEGFR/HER2/TS-IN-2 [2444364-04-7]
- Delivery Days Customer10
- CAS Number2444364-04-7
- CertificationResearch Use Only
- Molecular FormulaC26H21N7OS2
- Molecular Weight511.62
- Scientific DescriptionEGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 microM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 microM[1].
- SMILESN#CC1=C(N2N=C(C)C=C2C)N=C(SCC(NC3=NC4=C(S3)C=C(C)C=C4)=O)N=C1C5=CC=CC=C5
- UNSPSC12131703