EGFR/microtubule-IN-1
HY-161145
Molecular Weight492.32
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NameEGFR/microtubule-IN-1
- Delivery Days Customer14
- CertificationResearch Use Only
- Molecular FormulaC23H18BrN5O3
- Molecular Weight492.32
- Scientific DescriptionEGFR/microtubule-IN-1 (Compound 10c) is a dual inhibitor targeting EGFR and tubulin. The IC50 for inhibiting EGFR is 10.66 nM. EGFR/microtubule-IN-1 can reduce the phosphorylation levels of EGFR, AKT and ERK, hinder tubulin polymerization, and induce apoptosis[1].
- SMILESO=C(NC(NC1=C(OC)C=C(N=CN=C2NC3=CC=C(Br)C=C3)C2=C1)=O)C4=CC=CC=C4
- UNSPSC12352200