EHNA (hydrochloride)

MedChem Express

EHNA (hydrochloride) [58337-38-5]

10

58337-38-5

Research Use Only

99.61

C14H24ClN5O

313.83

EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2) ( IC 50 =4 microM) and adenosine deaminase (ADA) . EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)( IC 50 :0.8 microM (human), 2 microM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects [1] [2] .

CCCCCC[C@@](N1C2=C(C(N)=NC=N2)N=C1)([H])[C@H](O)C.Cl

-20°C

12352200