EHop-016

MedChem Express

EHop-016 [1380432-32-5]

10

1380432-32-5

Research Use Only

99.85

C25H30N6O

430.55

EHop-016 is a potent and selective Rac GTPase Rac1 and Rac3 inhibitor. EHop-016 inhibits Rac1 activity with an IC 50 of 1.1 microM in MDA-MB-435 cells. EHop-016 inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration [1] [2] .

CCN1C2=C(C3=C1C=CC=C3)C=C(NC4=NC(NCCCN5CCOCC5)=NC=C4)C=C2

-20°C,2°C to 8°C

12352200