EHP-101 (VCE- 004.8)

Biorbyt

EHP-101 (VCE- 004.8) [1818428-24-8]

10

1818428-24-8

Research Use Only

C28H35NO3

433.5824

EHP-101 (VCE-004.8) is an orally active, specific PPARgamma and CB2 receptor dual agonist. EHP-101 inhibits prolyl-hydroxylases (PHDs) and activates the HIF pathway. EHP-101 attenuates adipogenesis and prevents diet-induced obesity. EHP-101 (20?mg/kg/day; i.p.; for 3 weeks) induces a significant reduction in body weight gain, total fat mass, adipocyte volume and plasma triglycerides levels in HFD mice.

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12352200