The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA693996(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA693996(EID3 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200)
EID3 Antibody
CSB-PA693996
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetEID3
Overview
- SupplierCusabio
- Product NameEID3 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID493861
- Target nameEID3
- Target descriptionEP300 interacting inhibitor of differentiation 3
- Target synonymsNS4EB, NSE4B, NSMCE4B, EP300-interacting inhibitor of differentiation 3, E1A-like inhibitor of differentiation 3, EID-1-like inhibitor of differentiation 3, EID-3, NSE4 homolog B, non-SMC element 4 homolog B, non-structural maintenance of chromosomes element 4 homolog B, testis tissue sperm-binding protein Li 96mP
- HostRabbit
- IsotypeIgG
- Protein IDQ8N140
- Protein NameEP300-interacting inhibitor of differentiation 3
- Scientific DescriptionEID3 is highly expressed in testis and shows homology to a region of EID1 implicated in binding to CBP/p300. EID3 acts as a potent inhibitor of nuclear receptor transcriptional activity by a mechanism that is independent of direct interactions with nuclear receptors, including SHP. Furthermore, EID3 directly binds to and blocks the SRC-1 interacting domain of CBP, which has been implicated to act as the interaction surface for nuclear receptor co-activators. Consistent with this idea, EID3 prevents recruitment of CBP to a natural nuclear receptor-regulated promoter.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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