EIF2alpha activator 2 [1501618-04-7]

MedChem Express

EIF2alpha activator 2 [1501618-04-7]

10

1501618-04-7

Research Use Only

99.88

C21H20F6N2O2

446.39

EIF2alpha activator 2 (Compound 1) is an activator of eukaryotic initiation factor 2 alpha (eIF2alpha) phosphorylation. EIF2alpha activator 2 exhibits high potency in SRB cell proliferation assays (IC50=0.46 microM). EIF2alpha activator 2 exhibits antiproliferative activity againist K562 and PBMC cells with IC50s of 4.79 and 10.52 microM, respectively[1].

FC(F)(F)C(C=C1)=CC=C1O[C@H](CC2)CC[C@@H]2NC(NC3=CC(C(F)(F)F)=CC=C3)=O

-20°C,2°C to 8°C

12131703