eIF4A3-IN-1 [2095486-67-0]

MedChem Express

eIF4A3-IN-1 [2095486-67-0]

9

2095486-67-0

Research Use Only

99.96

C29H23BrClN5O2

588.88

eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 microM; Kd: 0.043 microM) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3].

ClC(C=C1)=CC=C1[C@@H]2N(C(C3=CC=C(Br)C=C3)=O)CCN(C(C4=C(C)N(C5=CC=CC(C#N)=C5)N=C4)=O)C2

-20°C,2°C to 8°C

12352200