eIF4E-IN-4

MedChem Express

eIF4E-IN-4 [1373822-39-9]

5

Research Use Only

C20H19ClN5O5P

475.82

eIF4E-IN-4 (Compound 33) is a selective inhibitor of eukaryotic initiation factor 4E (eIF4E) with biochemical activity value of 95 nM. eIF4E-IN-4 inhibits cap-dependent mRNA translation with an IC50 value of 2.5 microM. eIF4E-IN-4 can be used for breast cancer, colon cancer, and head and neck cancer study[1].

O=C1N=C(NC)NC2=C1N(CCOC3=CC=C(C=C3)Cl)C(C4=CC=C(P(O)(O)=O)C=C4)=N2

12131703