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ProductsBack/EIF4E2 antibody [N1C3]

EIF4E2 antibody [N1C3]

GTX103977
GeneTex
ApplicationsImmunoPrecipitation, Western Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse
TargetEIF4E2
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Overview

  • Supplier
    GeneTex
  • Product Name
    EIF4E2 antibody [N1C3]
  • Delivery Days Customer
    9
  • Applications
    ImmunoPrecipitation, Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.36 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9470
  • Target name
    EIF4E2
  • Target description
    eukaryotic translation initiation factor 4E family member 2
  • Target synonyms
    4EHP; 4E-LP; eIF-4E type 2; EIF4EL3; eIF4E-like cap-binding protein; eIF4E-like protein 4E-LP; eukaryotic translation initiation factor 4E homologous protein; eukaryotic translation initiation factor 4E type 2; eukaryotic translation initiation factor 4E-like 3; h4EHP; IF4e; mRNA cap-binding protein type 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO60573
  • Protein Name
    Eukaryotic translation initiation factor 4E type 2
  • Scientific Description
    Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression.
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  • Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP. Wiebe S et al., 2023 Jan 18, Mol Brain
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  • Kaposis sarcoma herpesvirus activates the hypoxia response to usurp HIF2alpha-dependent translation initiation for replication and oncogenesis. Mendez-Solis O et al., 2021 Dec 28, Cell Rep
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  • Local translation in nuclear condensate amyloid bodies. Theodoridis PR et al., 2021 Feb 16, Proc Natl Acad Sci U S A
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  • The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior. Wiebe S et al., 2020 Nov 23, Mol Autism
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  • Ribosome collisions trigger cis-acting feedback inhibition of translation initiation. Juszkiewicz S et al., 2020 Jul 13, Elife
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  • The Zebrafish Xenograft Platform-A Novel Tool for Modeling KSHV-Associated Diseases. Pringle ES et al., 2019 Dec 20, Viruses
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  • A threonyl-tRNA synthetase-mediated translation initiation machinery. Jeong SJ et al., 2019 Mar 22, Nat Commun
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  • Translational control of ERK signaling through miRNA/4EHP-directed silencing. Jafarnejad SM et al., 2018 Feb 7, Elife
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  • Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-beta signaling and malignant features in vitro and in vivo. Sese M et al., 2017 Dec 29, Oncotarget
    Read more