EIF4E2 antibody [N1C3]
GTX103977
ApplicationsImmunoPrecipitation, Western Blot
Product group Antibodies
TargetEIF4E2
Overview
- SupplierGeneTex
- Product NameEIF4E2 antibody [N1C3]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.36 mg/ml
- ConjugateUnconjugated
- Gene ID9470
- Target nameEIF4E2
- Target descriptioneukaryotic translation initiation factor 4E family member 2
- Target synonyms4E-LP, 4EHP, EIF4EL3, IF4e, h4EHP, eukaryotic translation initiation factor 4E type 2, eIF-4E type 2, eIF4E-like cap-binding protein, eIF4E-like protein 4E-LP, eukaryotic translation initiation factor 4E homologous protein, eukaryotic translation initiation factor 4E-like 3, mRNA cap-binding protein type 3
- HostRabbit
- IsotypeIgG
- Protein IDO60573
- Protein NameEukaryotic translation initiation factor 4E type 2
- Scientific DescriptionRecognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Naeli P, Zhang X, Snell PH, et al. The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression. J Cell Sci. 2023,136(19). doi: 10.1242/jcs.261286Read this paper
- Wiebe S, Huang Z, Ladak RJ, et al. Cell-type-specific translational control of spatial working memory by the cap-binding protein 4EHP. Mol Brain. 2023,16(1):9. doi: 10.1186/s13041-023-00995-2Read this paper
- Méndez-Solís O, Bendjennat M, Naipauer J, et al. Kaposi's sarcoma herpesvirus activates the hypoxia response to usurp HIF2α-dependent translation initiation for replication and oncogenesis. Cell Rep. 2021,37(13):110144. doi: 10.1016/j.celrep.2021.110144Read this paper
- Theodoridis PR, Bokros M, Marijan D, et al. Local translation in nuclear condensate amyloid bodies. Proc Natl Acad Sci U S A. 2021,118(7). doi: 10.1073/pnas.2014457118Read this paper
- Wiebe S, Meng XQ, Kim SH, et al. The eIF4E homolog 4EHP (eIF4E2) regulates hippocampal long-term depression and impacts social behavior. Mol Autism. 2020,11(1):92. doi: 10.1186/s13229-020-00394-7Read this paper
- Juszkiewicz S, Slodkowicz G, Lin Z, et al. Ribosome collisions trigger cis-acting feedback inhibition of translation initiation. Elife. 2020,9. doi: 10.7554/eLife.60038Read this paper
- Pringle ES, Wertman J, Melong N, et al. The Zebrafish Xenograft Platform-A Novel Tool for Modeling KSHV-Associated Diseases. Viruses. 2019,12(1). doi: 10.3390/v12010012Read this paper
- Jeong SJ, Park S, Nguyen LT, et al. A threonyl-tRNA synthetase-mediated translation initiation machinery. Nat Commun. 2019,10(1):1357. doi: 10.1038/s41467-019-09086-0Read this paper
- Jafarnejad SM, Chapat C, Matta-Camacho E, et al. Translational control of ERK signaling through miRNA/4EHP-directed silencing. Elife. 2018,7. doi: 10.7554/eLife.35034Read this paper
- Sesé M, Fuentes P, Esteve-Codina A, et al. Hypoxia-mediated translational activation of ITGB3 in breast cancer cells enhances TGF-β signaling and malignant features in vitro and in vivo. Oncotarget. 2017,8(70):114856-114876. doi: 10.18632/oncotarget.23145Read this paper
Datasheet
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