eIF4EBP1 Rabbit mAb

Biorbyt

eIF4EBP1 Rabbit mAb

10

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 FC, ICC, IHC, IP, WB

Research Use Only

Monoclonal

Unconjugated

EIF4EBP1

eukaryotic translation initiation factor 4E binding protein 1

4E-BP1, 4EBP1, BP-1, PHAS-I, eukaryotic translation initiation factor 4E-binding protein 1, eIF4E-binding protein 1, phosphorylated heat- and acid-stable protein regulated by insulin 1

Rabbit

IgG

Translation repressor protein 4E-BP1 (also known as PHAS-1) inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. Hyperphosphorylation of 4E-BP1 disrupts this interaction and results in activation of cap-dependent translation. Both the PI3 kinase/Akt pathway and FRAP/mTOR kinase regulate 4E-BP1 activity.

Human, Mouse, Rat

-20°C,2°C to 8°C

12352203