EIF4G (phospho Ser1231) antibody

GeneTex

EIF4G (phospho Ser1231) antibody - Orthogonal Validated

9

WB: 1:500 - 1:1000. IHC-P: 1:50 - 1:100. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

EIF4G1

eukaryotic translation initiation factor 4 gamma 1

EIF4F; EIF4G; EIF-4G1; EIF4-gamma; eIF-4-gamma 1; EIF4GI; eucaryotic translation initiation factor 4G; eukaryotic translation initiation factor 4 gamma 1; P220; PARK18

Rabbit

IgG

Eukaryotic translation initiation factor 4 gamma 1

The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]

-20°C or -80°C,2°C to 8°C

12352203