EIF4G2 Antibody

Cusabio

EIF4G2 Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

EIF4G2

eukaryotic translation initiation factor 4 gamma 2

AAG1, DAP5, NAT1, P97, eukaryotic translation initiation factor 4 gamma 2, DAP-5, aging-associated protein 1, death-associated protein 5, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, eukaryotic translation initiation factor 4G-like 1

Rabbit

IgG

Eukaryotic translation initiation factor 4 gamma 2

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Human, Mouse

-20°C or -80°C

41116161